Gene Mutations May Predict Melanoma Response to Immunotherapies

Douglas Johnson, M.D.

Christine Lovly, M.D., Ph.D.

Melanoma patients whose tumors test positive for mutations in the NRAS gene were more likely to benefit from new immunotherapy drugs, according to a new study led by Vanderbilt-Ingram Cancer Center (VICC) investigators.

Douglas Johnson, M.D., assistant professor of Medicine, and Christine Lovly, M.D., Ph.D., assistant professor of Medicine and Cancer Biology, are co-first authors of the study, conducted in conjunction with colleagues from Memorial Sloan Kettering Cancer Center (MSKCC), New York, and Massachusetts General Hospital (MGH), Boston. The study was funded in part by the T.J. Martell Foundation and published in Cancer Immunology Research.

“We studied a small group of patients but the results were quite suggestive,” Johnson said. “This study highlights the need to find predictive markers that can help us understand which patients will respond to therapy.”

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Dr. Sandeep Kapoor – Skin Cancer Prevention and Awareness at Bonnaroo Music Festival

Dr. Sandeep Kapoor with the T.J. Martell Foundation at Bonnaroo

I would like to extend a warm thank you to Laura Heatherly of the T.J. Martell Foundation for asking me to conduct a skin cancer awareness program at the Bonnaroo Music Festival in Manchester,Tennessee.

As a primary care physician, I truly enjoy reaching out to the community to educate the public on the importance of cancer prevention and early detection. We had an enthusiastic audience that spanned many age groups who were interested in learning how to protect themselves from the dangers of the sun and how to check themselves for early signs of skin cancer.

On behalf of he board of directors of the Ronnie James Dio Stand Up and Shout Cancer Fund, we appreciate our collaboration with the T.J. Martell Foundation and plan to be present at many more outdoor music festivals to spread the word about skin cancer prevention.

Cancer prevention and early detection saves lives!

Check Yourself for Cancer Today!

Sandeep Kapoor, MD

Co-Founder/Medical Director

The Ronnie James Dio Stand Up And Shout Cancer Fund

www.diocancerfund.org